Redefining Separation for Biomanufacturing
SPM develops next-generation separation technologies for biomolecules and bioparticles.
From Kyoto to the World
SPM Inc. is a Kyoto-based biotechnology start-up commercializing a novel separation platform based on Spongy Monolith technology originally developed at Kyoto University.
Why SPM?
Separation shouldn't be the bottleneck.
The growing demand for biopharmaceuticals and advanced biological materials is creating new challenges for conventional separation technologies.
Large and complex materials such as antibodies, extracellular vesicles, RNA, viruses, and cells require separation processes that are faster, more permeable, and more versatile.
SPM offers a new approach.
With its unique spongy monolithic structure and highly reactive surface, SPM combines:
High Flow Large through-pores enable highly permeable separation.
Low Pressure Efficient flow through interconnected macropores.
Functionalization Reactive epoxide groups enable versatile ligand immobilization.
Scalability A flexible polymer platform that can be formed into various formats.
What We Enable
A versatile separation platform for the next generation of bioprocessing.
Antibody & Protein Purification
Faster affinity purification with high permeability.
SPM combines large through-pores with immobilized protein ligands to enable rapid and selective purification of antibodies and other proteins.
Extracellular Vesicle Isolation
Selective separation of EVs from complex biological samples.
SPM can be functionalized with affinity ligands or inorganic materials to capture extracellular vesicles efficiently while maintaining high permeability.
Large Biological Particles
Expanding separation beyond conventional molecules.
The macroporous structure of SPM provides a platform for separating large and complex biological materials, including viruses and other bioparticles.
Custom Separation Platforms
Designed around your target.
The SPM platform can be modified with different ligands and functional groups, enabling customized separation solutions for emerging applications.
Let's transform separation together.
We are looking for partners in biopharmaceutical manufacturing, extracellular vesicles, life science research, and related fields.
